xeljanz for rheumatoid arthritis

Exploring the Efficacy of Xeljanz in Treating Rheumatoid Arthritis

Xeljanz is an innovative oral medication designed to treat Rheumatoid Arthritis. It works by inhibiting the body's overactive immune response, reducing inflammation and pain. With Xeljanz, you can regain control over your mobility and enjoy a significantly improved quality of life. Consult your doctor today to see if Xeljanz is right for you.

Product Type Medication
Brand Xeljanz
Purpose Treatment for Rheumatoid Arthritis
Active Ingredient Tofacitinib
Dosage Form Tablet
Route of Administration Oral
Prescription Required Yes
Manufacturer Pfizer
Xeljanz | Uses, How It Works, Effectiveness and Safety AlertsMore Bad Safety News for Xeljanz | MedPage TodayXeljanz Study Raises Safety Concerns About Heart and Cancer RisksStudy: Rheumatoid Arthritis Drug May Increase Cardiovascular, Cancer RisksBlack Box Warning for Xeljanz: High Doses Can Be DangerousWhat is Xeljanz XR used for? - Top Class ActionsORAL-Shift: Tofacitinib noninferior to combination with methotrexate in RATofacitinib - Wikipedia

Understanding Xeljanz

Xeljanz, scientifically known as Tofacitinib, is a Janus kinase (JAK) inhibitor used for treating certain types of arthritis. It is manufactured by the pharmaceutical company, Pfizer. Read more

How Xeljanz Works

Xeljanz works by blocking the activity of enzymes known as Janus kinases. These enzymes play a pivotal role in the inflammation process that is characteristic of rheumatoid arthritis. Read more

Xeljanz for Rheumatoid Arthritis

Xeljanz is FDA-approved for treating adults with moderate to severe rheumatoid arthritis who have not responded well to methotrexate. It can be used alone or with other non-biologic disease-modifying anti-rheumatic drugs (DMARDs). Read more

Dosage and Administration

Xeljanz is available as a pill, taken orally. The typical dosage is 5 mg twice daily, but a higher dosage of 11 mg once daily may be recommended for certain patients. Read more xeljanz for rheumatoid arthritis

Potential Side Effects

As with any medication, Xeljanz can have side effects. Common side effects include respiratory infections, headaches, and diarrhea. More serious risks include blood clots, cancers, and serious infections. Read more

Xeljanz and the Immune System

Xeljanz can lower the ability of the immune system to fight infections. Thus, patients should be screened for tuberculosis and other infections prior to starting the medication. Read more

Xeljanz and Pregnancy

Women who are pregnant or planning to become pregnant should discuss the potential risks and benefits with their healthcare provider. Xeljanz may potentially cause harm to the unborn baby. Read more

Monitoring While Taking Xeljanz

Regular monitoring of blood counts, liver enzymes, and cholesterol levels is recommended while taking Xeljanz. This can help detect any potential adverse effects early. Read more xeljanz for rheumatoid arthritis

Cost and Availability

The cost of Xeljanz can be high, although insurance and patient assistance programs may help offset the cost. It is available through prescription only in most countries. Read more

Xeljanz vs. Other Treatments

Xeljanz is often considered when other treatments have failed to provide adequate relief. Other treatment options for rheumatoid arthritis include nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and other DMARDs such as methotrexate. Read more

Vocabulary

Xeljanz – A prescription medication used to treat moderate to severe rheumatoid arthritis.

Rheumatoid Arthritis – A chronic inflammatory disorder that can affect more than just your joints, causing a painful swelling that can result in bone erosion and joint deformity.

Tofacitinib – The active ingredient in Xeljanz, which works by decreasing the activity of the immune system.

Immunosuppressant – A type of drug that lowers the body's ability to reject a transplanted organ, also used in treating autoimmune diseases.

Inflammation – A protective response by the body to injury or disease, marked by redness, heat, swelling, and pain.

JAK inhibitors – A type of medication that functions by inhibiting the activity of one or more of the Janus kinase family of enzymes (JAK1, JAK2, JAK3, TYK2), thereby interfering with the JAK-STAT signaling pathway.

JAK-STAT signaling pathway – A chain of interactions between proteins in a cell, and is involved in processes such as immunity, cell division, cell death, and tumor formation.

Methotrexate – A common drug used to treat rheumatoid arthritis, often in combination with other medications.

Biologic drugs – A type of DMARD used to reduce inflammation and prevent joint damage in rheumatoid arthritis.

Disease-modifying antirheumatic drugs (DMARDs) – A category of medications used in people with conditions that affect the immune system, such as rheumatoid arthritis.

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) – A class of drugs that provides analgesic and antipyretic effects, and, in higher doses, anti-inflammatory effects.

Corticosteroids – A class of drug that lowers inflammation in the body and reduces immune system activity.

Autoimmune Disease – A condition in which your immune system mistakenly attacks your body.

Chronic Disease – A long-lasting condition that can be controlled but not cured.

Joint Deformity – A condition caused by damage to the joint, often due to arthritis.

Synovial Fluid – The clear liquid that lubricates the joints and tendons.

Synovitis – The inflammation of the synovial membrane that lines joints.

Erosions – In rheumatoid arthritis, refers to the wearing away of bone within the joint.

Rheumatoid Factor – An antibody that can be detected in the blood of rheumatoid arthritis patients.

Anti-Cyclic Citrullinated Peptide (Anti-CCP) – Antibodies that are often detected in the blood of people with rheumatoid arthritis.

Rheumatoid Nodules – Firm lumps of tissue that can form under the skin of patients with rheumatoid arthritis.

Systemic Disease – A disease that affects multiple organs or the entire body.

Fatigue – A common symptom in rheumatoid arthritis due to the body's chronic inflammatory state.

Physical Therapy – A type of treatment often used in managing rheumatoid arthritis symptoms.

Rheumatologist – A specialist doctor who diagnoses and treats diseases of the joints, muscles, and bones.

Arthroplasty – A surgical procedure to restore the function of a joint, often used in severe cases of rheumatoid arthritis.

Joint Replacement Surgery – A surgical procedure to replace a damaged joint with an artificial one.

Synovectomy – A type of surgery that removes a diseased joint lining.

Arthritis Flare-Up – A period of increased disease activity or worsening symptoms in people with arthritis.

Remission – A period of time when the symptoms of chronic or severe disease are reduced or disappear.

Read more

Xeljanz For Rheumatoid Arthritis Expected In Stores Soon : Shots - Health News : NPRXeljanz For Rheumatoid Arthritis Expected In Stores Soon : Shots - Health News : NPRXeljanz | Ease of Use Products | Arthritis FoundationXeljanz | Ease of Use Products | Arthritis FoundationXeljanz XR (tofacitinib citrate) Modified Release Tablets For the Treatment of Rheumatoid Arthritis - Clinical Trials ArenaXeljanz XR (tofacitinib citrate) Modified Release Tablets For the Treatment of Rheumatoid Arthritis - Clinical Trials ArenaXeljanz Edges Humira Just a Bit for Real-World RA Patients, Study Suggests | MedPage TodayXeljanz Edges Humira Just a Bit for Real-World RA Patients, Study Suggests | MedPage TodayXeljanz | Uses, How It Works, Effectiveness and Safety AlertsXeljanz | Uses, How It Works, Effectiveness and Safety AlertsPfizer's rheumatoid arthritis drug adds indication for ulcerative colitis < Pharma < Article - KBRPfizer's rheumatoid arthritis drug adds indication for ulcerative colitis < Pharma < Article - KBRMore Bad Safety News for Xeljanz | MedPage TodayMore Bad Safety News for Xeljanz | MedPage TodayXeljanz Study Raises Safety Concerns About Heart and Cancer RisksXeljanz Study Raises Safety Concerns About Heart and Cancer RisksXELJANZ® (tofacitinib citrate) Receives Marketing Authorisation in the European Union for the Treatment of Moderate to Severe Active Rheumatoid Arthritis (RA) | Business WireXELJANZ® (tofacitinib citrate) Receives Marketing Authorisation in the European Union for the Treatment of Moderate to Severe Active Rheumatoid Arthritis (RA) | Business WireXeljanz Side Effects | Blood Clot, Infection and Cancer RisksXeljanz Side Effects | Blood Clot, Infection and Cancer RisksFDA Alerts Clinicians and Public of Cardiac and Cancer Risks from Tofacitinib. — Donovan Hair ClinicFDA Alerts Clinicians and Public of Cardiac and Cancer Risks from Tofacitinib. — Donovan Hair ClinicXeljanz XR (tofacitinib citrate) Modified Release Tablets For the Treatment of Rheumatoid Arthritis - Clinical Trials ArenaXeljanz XR (tofacitinib citrate) Modified Release Tablets For the Treatment of Rheumatoid Arthritis - Clinical Trials ArenaXeljanz 5mg Tablet Price: UP To 45% Off | Xeljanz Cost | MagicinePharmaXeljanz 5mg Tablet Price: UP To 45% Off | Xeljanz Cost | MagicinePharmaXeljanz - MHM Law OfficesXeljanz - MHM Law OfficesStudy: Rheumatoid Arthritis Drug May Increase Cardiovascular, Cancer RisksStudy: Rheumatoid Arthritis Drug May Increase Cardiovascular, Cancer RisksBlack Box Warning for Xeljanz: High Doses Can Be DangerousBlack Box Warning for Xeljanz: High Doses Can Be DangerousXeljanz vs. Humira or Enbrel for Rheumatoid Arthritis - GoodRxXeljanz vs. Humira or Enbrel for Rheumatoid Arthritis - GoodRxXeljanz Rheum | Pfizer for ProfessionalsXeljanz Rheum | Pfizer for ProfessionalsThe People's PharmacyThe People's PharmacyFDA to review modified-release version of Pfizer's Xeljanz for rheumatoid arthritis | Fierce PharmaFDA to review modified-release version of Pfizer's Xeljanz for rheumatoid arthritis | Fierce Pharma